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Alzheimer's Disease and Folic Acid

One of the highlights of my teaching is to help nursing students feel comfortable when looking after patients with Dementia, be that Alzheimer's, Huntingdon's Chorea, etc.

But these conditions don't necessarily have to happen or they can be held back. There is a lot of research going on now, trying to relate the oxidative stress process with these conditions. Many patients are given "optimum" doses of anti-oxidants with almost unbelievable results. Here is another study, but this time using folic acid, a trace mineral. I want to recognize the research work of Joan Baumann, jwbaumann@sprint.ca  in Ontario, Canada, for keeping a sharp eye out for very helpful relevant research material. She always adds her "lay comments", which helps us all to connect the importance of the study findings to our own needs.

Joan writes:
Another piece to the puzzle of Alzheimer's Disease has been put into place. According to this report from the New England Journal of Medicine, a simple, economical prevention might be FOLIC ACID! The 1000mcgs of Folic Acid in our 3 Mega Antioxidants per day provides health benefits in so many areas.

Kind regards, Joan E. Baumann:

THE NEW ENGLAND JOURNAL OF MEDICINE
Volume 346, Issue 7: February 14, 2002
Plasma Homocysteine and Alzheimer's Disease

A cohort of 1092 elderly subjects who were free of dementia were studied prospectively. After a median of eight years of follow-up, dementia had developed in 111 subjects. Even after adjustment for other known risk factors, an elevated plasma total Homocysteine level at base line was an independent predictor of the development of clinical dementia, most cases of which were caused by Alzheimer's disease. The risk of Alzheimer's disease was nearly doubled for those with the highest plasma Homocysteine levels.

This prospective, observational study greatly strengthens the evidence for an association between the plasma Homocysteine level and the risk of dementia. Since folic acid supplementation can reduce plasma Homocysteine levels, this report suggests an intervention that may help prevent dementia.


June 2 /02

Karin.

If you would like more information on this topic, or if you would like to know if we could help you get some relief, please use this link to ask your health question or request more information on getting some help.
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Karin Henderson British Columbia, Canada (604) 463 8666
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